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How GLP-1 Medications Support Weight Loss Mechanism of Action of GLP-1 Medications GLP-1 medications mimic the action of the GLP-1 hormone, which is naturally produced in the intestines in response to food intake

Liraglutide (Saxenda, Victoza) Liraglutide was the first GLP-1 receptor agonist approved specifically for weight management

Its use in laboratory and clinical settings continues to expand

It happens when food moves too quickly from the stomach into the small intestine

The GLP-1 agonist exendin-4 attenuates self-administration of sweetened fat on fixed and progressive ratio schedules of reinforcement in rats

Abdominal pain in gastroparesis may respond less well to treatment [49, 71]